Cost comparison
NAD+ IV drips vs a daily NAD+ drink
A single NAD+ IV session commonly runs several hundred dollars and takes hours in a chair. Here is what you are actually paying for, where the IV genuinely differs, and what a daily oral precursor does instead.
Try your first box — $25Free US shipping · 30-day money-back guarantee
An NAD+ IV delivers NAD+ straight into the bloodstream, bypassing digestion — that is a real pharmacokinetic difference, and it is why clinics use it. It is also expensive, time-consuming and something you do occasionally rather than daily. An oral precursor like nicotinamide riboside takes the other route: a smaller amount, every single day, for about a dollar. Consistency is the trade you are making.*
What you are comparing
| NAD+ IV drip | simplyNAD+ daily packet | |
|---|---|---|
| Typical cost | Commonly several hundred dollars per session, varying widely by clinic and region | $25 first box — about $0.83 a day |
| Time per dose | Often 2–4 hours seated at a clinic | About 10 seconds, wherever you are |
| Frequency | Occasional; a course of sessions | Once a day, every day |
| Route | Intravenous — bypasses digestion entirely | Oral precursor your body converts to NAD+ |
| Booking required | Yes | No |
| Also includes | Varies by clinic | Quercetin phytosome, trans-resveratrol, PQQ |
We are not going to tell you IVs do not work, or that a packet is medically equivalent to an infusion. They are different routes of administration. What we will say plainly: for most people the barrier to an IV protocol is not whether it works, it is $400 and an afternoon, repeatedly.
Why oral precursors exist at all
NAD+ itself is a large, charged molecule that does not survive digestion well. An IV sidesteps that. The oral answer is to give the body a precursor it can assemble into NAD+ on its own — and published human trials show that oral nicotinamide riboside raises blood NAD+.1,2 Martens and colleagues ran that for six weeks in healthy middle-aged and older adults and reported it was well tolerated.3*
About $0.83 a day, no appointment
600mg nicotinamide riboside in one sweet berry packet. Rip it, drink it, done — no capsules, no clinic, no calendar.
Try your first box — $25 Free US shipping · 30-day money-back guaranteeThe honest caveats
- Different routes are not interchangeable. An infusion and an oral precursor do not produce the same blood curve. Anyone claiming a packet "replaces" an IV is overselling.
- Clinic pricing varies enormously. Get a real quote before comparing; the numbers you see quoted online range widely.
- Neither is a treatment. NAD+ supplements are not intended to diagnose, treat, cure or prevent any disease. If a clinic tells you otherwise, that is a red flag.*
Frequently asked
Is a daily NAD+ drink as good as an IV?
They are different routes of administration and we will not claim equivalence. An IV puts NAD+ directly into the bloodstream; an oral precursor gives your body the building block daily. The oral route's advantage is that you will actually keep doing it.
How much does an NAD+ IV cost?
It varies a lot by clinic and region, and is commonly several hundred dollars per session. Ask for a written quote, including how many sessions a course involves.
Can I do both?
People do. If you are working with a clinic, tell them what you are taking orally so they have the full picture.
Why is your product a liquid and not a capsule?
Because 600mg of NR plus quercetin, resveratrol and PQQ is several capsules' worth. A packet is one step, and the step people skip is the one they stop doing.
Does it need to be refrigerated?
No. Store the packets at room temperature, away from direct heat. Shake or squeeze before drinking — natural settling is normal.
References
- Trammell SAJ, Schmidt MS, Weidemann BJ, et al. Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nature Communications. 2016;7:12948.
- Airhart SE, Shireman LM, Risler LJ, et al. An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside and its effects on blood NAD+ levels in healthy volunteers. PLoS ONE. 2017;12(12):e0186459.
- Martens CR, Denman BA, Mazzo MR, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nature Communications. 2018;9:1286.
Keep reading
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. simplyNAD+ is a dietary supplement, not a medicine. If you are pregnant, nursing, taking medication or managing a health condition, speak with your doctor before use.